“First, commercially sponsored clinical trials report favourable conclusions about the sponsor’s drug or device 34 percent more frequently than non-commercially funded trials do. Moreover, when the principal investigator of a published clinical trial has financial ties to the manufacturer of the drug being studied-as is the case in two-thirds of published clinical trials-the odds are three and a half times greater that the study will report that the dug is effective. And amplifying the significant bias found in commercially sponsored studies, 97 percent of the studies most frequently cited in the literature are funded by the industry. This means that more than nineteen out of twenty of the studies having the greatest impact on doctors’ practice are commercially funded-and significantly more likely to show positive results for the sponsor’s product.”
John Abramson MD, MSc: ”sickening: How Big Pharma Broke American Health Care and How We Can Repair It”: Mariner Books 2022.