“Mutantism on the March” Chapter 41 “Dr. Zodiac Reveals a Secret”

Montenez continued his conversation with Dr. Zodiac, “The Greek Gods really began unravelling after the construction of various European empires. They lost the ability to control civilization as they had done in earlier times and of course the Greeks falling under Ottoman rule didn’t help their state of mind. Remember the Berlin Conference of 1870 where African fiefdoms were divvied up by European powers without regard to natural or tribal boundaries. Humanity in Europe was simply a gathering of greedy children grabbing all they could lay their hands on. Then there was hope with the Russian Revolution that man had finally seen the errors of their ways. Then that revolutionary spirit was broken with internal powerplays, the assassination of Trotsky, brutal collectivization and the slavery of the proletarian masses. Of course that brutal power crazed Stalin liquidated not only millions of people but the hope for a true revolution and slavery for the conquests of the USSR.

The night the bomb was dropped on Hiroshima was a dark time for the Greek Gods. It was about at that time the Greek Gods started thinking above leaving Earth. I tried to persuade them of their mission to aid humanity but they had no spirit left for that. Then the Korean and Vietnamese War were about the last straws. Then here on Samos the tourist explosion was the last straw. Arrogant, drunken and stupid tourists. A far as the Greek Gods were concerned it was as if humanity was engaging in one last fit of decadence before it self destructed. So   off they fled to Zlano, a quiet and peaceful dimension. It became their retirement home.”

Dr. Zodiac responded, “You remained at the drawbridge while we climbed into the ivory tower of nostalgic philosophy. This has caused me to depart from the Zlano dimension. I raised you like my own son. It pained me to leave you behind. I see their inherent selfishness with their rejection of the mutant Bertie Foonbean. Even the Friday night poetry readings and visits from aliens became boring. So I find myself here hoping I can help you in some way. But being upfront with you I am also on Earth because of a serial killer called The Zodiac Killer in California and Nevada. His deeds tarnish my name! I must defend my name. He carves astrology signs on his victims and leaves clues in code. There are rumours, even in Zlano, that I am this killer.

And as for Bertie Foonbean we have found an expert in mutantism called Squid, being a mutant himself, also specializes in the treatment of mutants if treatment is really an appropriate word to use. Squid has a reputation of helping humanity as you have probably heard of his work in Columbia and Nicaragua. You two should really mee. So far our messengers have failed to locate him although I am told they are hot on his trail. He sounds like an interesting chap.”

Poetry Break; “Ontario Disease Fascism”

               Ontario Disease Fascism

Yet another televised briefing by Premier Doug Ford
and his group of well meaning “Party Members”
dare we call them blackbooters?
stripping civil liberties like peeling a banana
for the good of the province
understandable perhaps due to an inadequately funded hospital system
result of many political decisions
you have  taken my job
you have taken away my right to socialize with my family
you have trapped me in a prison
again understandable…perhaps
it could be you felt you had no choice
do you remember Pierre Elliott Trudeau saying the Canadian government had no right to be in the bedrooms of the nation
Well Premier Ford you are all over my house
and your Solicitor General gives police unprecedented powers without any mention of “probable cause”!
shunt aside public civil rights
all in the name of a fight

Premier Ford you always said you’d cover our backs
but creating a new cadre of blackbooters
perhaps you meant a stab in the back?
always the same story of optimism
but quite frankly with your yoyoism on shutting and reopening
you blew it and we all are paying the price
Trump, Putin and Xi Jinping all have the reasons
and now you have yours
always of course for a “good cause”
and the news coverage shows all the good citizens saying they agree
like lambs to the slaughter
and of course we’ll have the right to vote as we see fit
assuming of course the polls are closed by the advice of the Public Health Table
whomever they may be but we know they are not elected

Robert K. Stephen

Jon Kabat-Zinn “Full Catastrophe Living”; Mindfulness and Yoga

“Yoga is also good exercise because it is a type of full-body conditioning. It improves strength, balance, and flexibility in the entire body. It’s like swimming, in that every part of your body is involved and benefits. It can even have cardiovascular benefits when done vigorously. But in MBSR (mindfulness bases stress reduction) the way we do it is not cardiovascular exercise. We do it primarily for stretching and strengthening your muscles and joints, to wake up the body to its full range of motion and potential for movement and balance.”

Passage of the Day: Marguerite de Navarre (1492-1549) “The Heptameron”: Love and the monarchy

“ ‘The reason is” said Dagoucin, ‘that in order to maintain peace in the state, consideration is given to the rank of families, the seniority of individuals and the provisions of the law, and not to man’s love and virtue, in order that the monarchy should not be undermined. Consequently, in marriages between social equals which are contracted according to the judgement of the family concerned, the partners are often so different in the feelings of the heart and in temperament that far from entering into a state leading to salvation, the frequently find themselves on the outskirts of Hell’ “

Dr. Walensky and Dr. Fauci Speak at White House Press Briefing

Press Briefing by White House COVID-19 Response Team and Public Health Officials

MARCH 29, 2021 • PRESS BRIEFINGS

Via Teleconference

11:04 A.M. EDT

ACTING ADMINISTRATION SLAVITT:  Good morning.  Thank you for joining us.  Today, I’m joined by Drs. Walensky and Fauci.  The cases of COVID-19 are once again on the rise.  Dr. Walensky will highlight the public health consequences and strong public health recommendations for the next few weeks. 

In the meantime, we are vaccinating the country as quickly as humanly possible, now averaging 2.7 million vaccinations over the last seven days.  Yesterday, the U.S. reported 3.28 million vaccinations.  This is significant progress toward the President’s now doubled vaccination goal of 200 million shots in his first 100 days in office and toward our ultimate goal of getting all Americans vaccinated as equitably and efficiently as possible. 

As we said on Friday, vaccine manufacturers report to us that they remain on track to meet their targets by the end of the month.  And Moderna announced that it had released its 100 millionth dose this morning.

As of today, 73 percent of seniors have now received their first dose.  And 36 percent — more than 1 in 3 adults — have received their first dose.  That’s 36 percent of adults.  Overall, now more than 50 million Americans — approaching 1 in 5 adults — are fully vaccinated. 

The effort is an immensely complex endeavor, and pulling it off requires tens of thousands of people doing their part.  And we are grateful to everybody on the frontlines of this pandemic.

This is good news.  We’re headed in the right direction.  But we can’t slow down.  Millions remain unvaccinated and at risk. 

We need to keep increasing vaccine supply, the number of vaccinators in the field, and adding more safe and convenient places for Americans to get vaccinated, especially as more states begin to open vaccine eligibility to all adults.

Now, today, as part of this ongoing effort to help meet the President’s goal of 200 million shots in his first 100 days, we’re announcing two new federally run mass vaccination sites.

The first is at America’s Center Convention Complex in St. Louis, Missouri, and the second is at Roosevelt High School in Gary, Indiana.  Soon, local residents will be able to get a shot at both of these sites.  And together, they will be capable of administering 6,000 shots per day.  

We now have 21 operational sites that have already administered a combined 1.7 million shots.  These sites are run by the federal government in close partnership with state and local officials.  And they are placed in communities with high risk, according to CDC’s social vulnerability index, with a direct goal of ensuring we’re equitably distributing vaccines and reaching communities that have been hurt the most by the pandemic. 

Before I turn it over to Dr. Walensky, I want to close by reiterating what the President said last Thursday: Help is here, and hope is around the corner.  But we’re not there yet, as Dr. Walensky will report.  The worst thing we could do now would be to let up.  We cannot get complacent.  We cannot let our guard down. 

It’s imperative for us to stick to the science and follow public health guidance.  That means continuing to wear masks; masks save lives.  It means continuing to socially distance; socially distancing saves lives.  And it means getting vaccinated when it’s your turn, because getting vaccinated saves lives — not just your own, but your family and friends and neighbors too. 

With that, I’m going to turn this over to Dr. Walensky and then to Dr. Fauci for some important updates.

DR. WALENSKY:  Thank you, Andy.  I’m glad to be back with you all today.  I want to begin with an overview of the continuing concerning trends in the data.  Yesterday, we in the United States surpassed 30 million cases of COVID-19.  CDC’s most recent data show that the seven-day average of new cases is slightly less than 60,000 cases per day.  This is a 10 percent increase compared to the prior seven-day period. 

Hospitalizations have also increased.  The most recent seven-day average, about 48 admi- — 4,800 admissions per day, is up from 4,600 admissions per day in the prior seven-day period.  And deaths, which typically lag behind cases and hospitalizations, have now started to rise, increasing nearly 3 percent to a seven-day average of approximately 1,000 deaths per day.

When I first started at CDC about two months ago, I made a promise to you: I would tell you the truth, even if it was not the news we wanted to hear.  Now is one of those times when I have to share the truth and I have to hope and trust you all listen.

I’m going to pause here.  I’m going to lose the script.  And I’m going to reflect on the recurring feeling I have of impending doom.  We have so much to look forward to, so much promise and potential of where we are, and so much reason for hope, but right now I’m scared.  I know what it’s like as a physician to stand in that patient room — gowned, gloved, masked, shielded — and to be the last person to touch someone else’s loved one because their loved one couldn’t be there.

I know what it’s like when you’re the physician, when you’re the healthcare provider and you’re worried that you don’t have the resources to take care of the patients in front of you.  I know that feeling of nausea when you read the crisis standards of care and you wonder whether there are going to be enough ventilators to go around and who’s going to make that choice.  And I know what it’s like to pull up to your hospital every day and see the extra morgue sitting outside.

I didn’t know at the time when it was — when it would stop; we didn’t have the science to tell us.  We were just scared.  We have come such a long way.  Three historic scientific breakthrough vaccines, and we are rolling them out so very fast. 

So I’m speaking today not necessarily as your CDC director — not only as your CDC director but as a wife, as a mother, as a daughter to ask you to just please hold on a little while longer.  I so badly want to be done.  I know you all so badly want to be done.  We are just almost there but not quite yet.  And so I’m asking you to just hold on a little longer, to get vaccinated when you can so that all of those people that we all love will still be here when this pandemic ends.

The trajectory of the pandemic in the United States looks similar to many other countries in Europe, including Germany, Italy, and France looked like just a few weeks ago.  And since that time, those countries have experienced a consistent and worrying spike in cases.  We are not powerless; we can change this trajectory of the pandemic.  But it will take all of us, recommitting to following the public health prevention strategies consistently, while we work to get the American public vaccinated. 

I’m calling on our elected officials, our faith-based communities, our civic leaders, and our other influencers in communities across the nation, and I’m calling on every single one of you to sound the alarm to carry these messages into your community and your spheres of influence.  We do not have the luxury of inaction.  For the health of our country, we must work together now to prevent a fourth surge. 

And after that honest plea, I want to reflect on so many reasons we have to be hopeful and why your actions today can get us out of this soon.  As I shared last week, we continue to get more and more real-world evidence on the protection of COVID-19 vaccines provide.  And CDC scientists have been working since these vaccines were first authorized to expand the evidence supporting their effectiveness. 

Today, I’m excited to share information about a new CDC-led study that’s being published in the MMWR.  This study assesses the real-world effectiveness of the Pfizer and Moderna vaccines in preventing infections among nearly 4,000 healthcare personnel, first responders, and other essential workers in six states from mid-December to mid-March. 

The study found that the risk of infection was reduced by 90 percent after individuals received the two recommended doses of the vaccine.  The study also found that people starting to get a protective effect, even after the first dose, the risk of infection decreased by 80 percent after two weeks.  Findings of this are all consistent with the clinical trial data. 

Importantly, people in the study received self-collected nasal swabs each week for laboratory testing, allowing CDC to look at evidence of COVID-19 infection whether or not people had symptoms. 

A small number of infections were asymptomatic; however, most infections occurred among people whose infections were identified by testing before they developed symptoms or knew they were infected.  This study also demonstrates that two vaccines can reduce the risk of COVID-19 infections, not just in symptomatic infections but also in asymptomatic or pre-symptomatic infections. 

This study is tremendously encouraging and complements other recent studies published in the New England Journal of Medicine, and discussed by Dr. Fauci last week, among similar populations at a high risk of exposure to COVID-19 because of their occupations.  These findings also underscore the importance of getting both of the recommended doses of the vaccine in order to get the greatest level of protection against COVID-19, especially as our concerns about variants escalate.

Our national vaccination efforts are working.  As of yesterday, over 93 million people have received one or more doses of vaccine, and over 51 million people have been fully vaccinated.  And CDC is collaborating across the government with our state, territorial, local, and tribal partners to get vaccines to communities and to get vaccinations into arms as quickly as possible through a multitude of channels, including the Federal Retail Pharmacy Program, through FEMA’s community vaccination centers and mobile clinics, and through HRSA’s Community Health Center Program. 

These efforts are rapidly advancing our goal to getting 200 million shots in arms during the first 100 days of this administration.  Over one in three adults in this country have already received one dose. 

Finally, I want to share today that CDC is making important updates to the list of underlying medical conditions that can increase risk of severe COVID-19 outcomes.  This update is keeping in — up with my commitment to lead with science, to have clear information on our website, and to better describe the science underlying these conditions. 

After a thorough review of the evidence, we have simplified the list of underlying conditions for consumers and created a new page for healthcare providers.  This will make it easier for patients and the public and providers to understand the important information related to their underlying medical conditions and its potential impact on COVID-19 severity. 

We’ve also updated the list of underlying medical conditions to include substance use disorders, based on evidence that having these conditions can increase risk of severe illness or death from COVID-19.

You can now visit the CDC website to learn more about these underlying medical conditions and the science evidence used to support their inclusion in the list. 

I reach out to you both with my concerns — my concerns and also my hope so that you can all be here to hear this message, healthy and vaccinated in the months ahead. 

Thank you.  I will now turn things over to Dr. Fauci.

DR. FAUCI:  Thank you very much, Dr. Walensky.  I’d like to make a few comments over the next couple of minutes that extend what you just heard from Dr. Walensky, and that is the importance of vaccination to prevent severe disease and why we cannot pull back on our mitigation efforts.  This is a paper from the Annals of Internal Medicine from some time ago which showed that about one third of people with SAR-CoV-2 infection never develop symptoms.  That’s the good news. 

Next slide.

Of those who do develop symptoms, about 80 percent have mild to moderate symptoms, but about 20 percent or more have severe disease with case fatality rates varying from a few percent to up to 20 percent for those requiring mechanical ventilation.

Now let me show you something that is very dramatic.  If you look at the multi-system manifestations of COVID-19, they are multitudinous, the most important and common of which is the acute respiratory distress syndrome.  But we know now there are neurological disorders, cardiac dysfunction, acute kidney injury, hypercoagulability.  Bottom line: This is a very serious disease, which has already led to the death of about 550,000 people in the United States. 

Next slide.

This slide is very dramatic.  If you look on the left-hand part of the slide, it’s a normal CT scan of the lung — the area that looks black and dark on normal lung because there are air spaces.  On the right-hand side of the slide is a patient that I made rounds on at the NIH Clinical Center last week.  If you look at this, even a non-physician, non-radiologist can determine that there’s something very, very wrong with the lungs on the right-hand side, with the white blotches being infiltration of the lung; that even with the patient being under the top medical care that we’re giving them at our hospital still may very likely have residual scarring of the lung after improvement. 

Next slide.

This is another patient we serve at the Clinical Center who developed a brain infarct, as shown on the left-hand part of the slide, with the arrow pointing to the infarcted part of the brain. 

Bottom line, as Dr. Walensky said in her experience at Mass General, the same at the NIH Clinical Center: This is a very, very bad disease. 

The fundamentals to prevent acquiring this are the public health measures that Dr. Walensky mentioned but also vaccination.  Absolutely critical. 

Next slide.

If you look at the prevention of hospitalization and death among the five vaccines on the left-hand part of the slide, with one exception of a hospitalized patient in the vaccine arm of the Moderna study, virtually 100 percent protection against hospitalizations and death.  In other words, you can prevent what I showed you on the previous two slides by getting vaccinated. 

And on the last slide, what you see in red is hospitalizations going down, as in the blue bars vaccinating people going up. 

The bottom line: Hang in there, as Dr. Walensky said.  We really need to hold on to the public health measures as we get more and more people from two- to three-plus million people vaccinated every day.  It will be a race between the vaccine and what’s going on with the dynamics of the outbreak.  And we can win this by just hanging in there a bit longer.

Back to you, Andy.

ACTING ADMINISTRATOR SLAVITT:  Thank you, Dr. Fauci and Dr. Walensky.  Let’s go to questions.

MODERATOR:  The first question will go to Ed O’Keefe at CBS.

Q    Thank you, guys, for doing this again as always.  I had one other question, but given what the Director just said, I guess I want to follow up a little bit and ask — if I heard you correctly, you said you’re concerned about “impending doom.”  What is it that you saw in the data that is causing you to sort of start to feel this way again? 

And then was curious if you guys can discuss what is the government or the administration’s current role in issuing these so-called “passports” or “certificates”?  And why is it taking a little while longer for the U.S. to do that when places like Japan and China and the EU are further along?

ACTING ADMINISTRATOR SLAVITT:  So, Dr. Walensky, why don’t you take the first question, and I’ll endeavor to take the second?

DR. WALENSKY:  When we were stagnating at around 40- to 50,000 cases a day for a couple of weeks there, we didn’t see trends going down anymore, but things were sort of holding steady.  What we’ve seen over the last week or so is a steady rise in cases.  We’re now in the 60- to 70,000 range.  And when we see that uptick in cases, what we have seen before is that things really have a tendency to surge and surge big.

We know that cases sometimes can be a week or two behind the behaviors that lead to those cases, the mixing that leads to those cases.  We know that travel is up, and I just worry that we will see the surges that we saw over the summer and over the winter again.

ACTING ADMINISTRATOR SLAVITT:  Thank you.  And I’ll take your second question.  Let me begin with this: We recognize this is a tricky and important subject, but the core here is that Americans, like people around the world, who are vaccinated will want to be able to demonstrate that vaccination in various forms.

This is going to hit all — all parts of society.  And so, naturally, the government is involved.  But unlike other parts of the world, the government here is not viewing its role as the place to create a passport, nor a place to hold the data of citizens. 

We view this as something that the private sector is doing and will do.  What’s important to us — and we’re leading an interagency process right now to go through these details — are that some important criteria be met with these credentials.

Number one, that there is equitable access; that means whether or not people have access to technology or whether they don’t.  It’s also important that we recognize that there are still many, many millions and millions of Americans that have not yet been vaccinated.  So that’s a fundamental equity issue.

Privacy of the information, security of the information, and a marketplace of solutions are all things that are part of what we believe in, as is the ability for people to access this free and in multiple languages. 

So I think you will see more from us as we complete our interagency process.  But this is not slowing down the process in any way, even though the government has its own needs and so does the private sector.  And the private sector and other groups working together are marching in that direction. 

It is important for us, and it will be — we will be very clear about how that will happen, that the guidelines that I just talked about are part of that process. 

Next question. 

MODERATOR:  Next we’ll go to Chris Megerian at the Los Angeles Times. 

Q    Hi, everybody.  I wanted to see if you can specifically speak to why this rise is happening.  Are you seeing it in restaurants?  Are you seeing it in people’s homes?  Are you seeing it in the workplaces?  And also, the administration has been urging people to be careful, you know, since the new president took office in January.  Why is the administration’s efforts not working in this situation? 

ACTING ADMINISTRATOR SLAVITT:  Let’s go around here, maybe start with you, Dr. Walensky, and then, Dr. Fauci, you can come after that. 

DR. WALENSKY:  Yeah, I think we’re investigating some of these outbreaks at a local level with individual states.  I think we are seeing that many of these states are opening up at levels that we wouldn’t necessarily recommend.  I am working with the governors.  I will be speaking with them tomorrow to try and buckle down on trying to refrain from opening up too fast, you know, in the context of the fact that we’re scaling up these vaccines. 

I think we’ve seen an uptick in travel.  We have seen an uptick in travel.  Much more travel is happening.  I think people want to be done with this.  As I mentioned, I too want to be done with this.  The thing that’s different this time is that we actually have it in our power to be done with the scale of the vaccination.  And that will be so much slower if we have another surge to deal with as well. 

ACTING ADMINISTRATOR SLAVITT:  Dr. Fauci, anything you want to add to that?

DR. FAUCI:  Yeah.  I think everyone really needs to appreciate that we really do want to get back to normal as quickly as we possibly can.  But I think one of the explanations, in answer to the question that we just heard, is that if we open up completely now, that is premature given the level of infection that Dr. Walensky described in her formal presentation. 

So that’s the reason why we’re essentially pleading with people, even though we have — all of us — an urge, particularly with the warm weather coming, to just cut loose.  We’ve just got to hang in there a bit longer. 

And I think the reason we’re seeing this plateauing and a bit of a little increase that we hope doesn’t turn into a surge is because we are really doing things prematurely right now with regard to opening up.

ACTING ADMINISTRATOR SLAVITT:  Chris, will you —

DR. WALENSKY:  Perhaps one other —

ACTING ADMINISTRATOR SLAVITT:  Please, Dr. Walensky.

DR. WALENSKY:  Perhaps one other comment on that, and that is our concern about variants.  We’ve been watching the variants really carefully.  We know about 26 percent of all sequenced virus is now the B117 variant.  It is more transmissible than the wild-type variant.  So we’re watching that carefully, and that may be one of the reasons in terms — if people are not doing the things — masking, distancing — to protect themselves, this variant is probably less forgiving, and more infections will occur. 

ACTING ADMINISTRATOR SLAVITT:  Chris, we recognize that it’s difficult for people to both feel optimism and display caution at the same time.  We believe one of the most important pieces of this formula — and that the public tells us — is just clear, consistent, honest, direct, straightforward information. 

That’s why in these briefings is you’ll see Dr. Fauci talks very directly and shows data very directly, and Dr. Walensky presents information and recommendations very clearly.  It’s not always what people want to hear, but it’s always directly what people, for the most part, say that they’re looking for, which is just the straight story that they can assimilate and help them make decisions.

We hope that they’re hearing quite clearly a consistent message today, which is that we don’t have a long time, necessarily, to be in this state with, but we are not out of this pandemic yet.  If we do our jobs, it can be short as possible. 

Next question. 

MODERATOR:  Next we’ll go to Zeke Miller at the AP.

Q    Thank you all for doing the call.  Just a couple of quick follow-ups on all these points.  Can you speak to specifically why you don’t think the federal government is the right place to have set up a vaccination passport?  I mean, given the data privacy concerns and widespread adoption and equity concerns that you’ve just raised, Andy, should — wouldn’t the federal government be best positioned to respond to those?

In the case of — and then, separately, when it comes to the travel and the virus guidance, Dr. Walensky, Dr. Fauci, should we expect to be hearing more from the President about the need for people to double down on these restrictions?  We’ve heard him (inaudible).  We have not heard the President, sort of, lead the charge on that.

And then finally — Andy, sorry — and sorry, Kevin, for the third question here — can you speak to how the 11 million doses of J&J vaccine that are expected to be shipped this week will be sent?  Will they be allocated to the existing formula or will they be deployed in a different — in a different way?

ACTING ADMINISTRATOR SLAVITT:  Okay, so we have vaccine passport; we have travel guidelines, which I will route to you, Dr. Walensky; and then we have 11 million J&J doses.  Usually, I forget the third question if there’s a third question by the time we get to it.

You know, relative to the vaccine passport, we think it’s very important for the public — job one is for the public to become comfortable if they’re considering taking a vaccine — why that is in their best interest.  And we think all of the data and all of the results and all the impact in the slide that Dr. Fauci showed are the preponderance of the reason we’re just so fortunate to be in this position relative to these vaccines.

We do know that there is a segment of the population that is concerned that the government will play too heavy-handed of a role in monitoring their vaccinations and that mandates will be coming from the federal government and important — in point of fact, it would discourage people to feel like that was the role we’re playing.

So we think we can have the best of all worlds.  We think we can essentially put forward guidelines and guidance.  And given the federal government’s source and role in society for everything from the TSA, to the VA, to Departments of Health and Human Services, the CDC — I could go on and on — you know, we have a major impact in what we’ll get done.

So we’re putting forward our principles very clearly.  We will be even more clear in the time ahead.  And we believe, based on everything we know, that that will influence the outcome in the way we describe.

So, with that, let me ask you, Dr. Walensky, to — if you can address the travel question.

DR. WALENSKY:  Yeah, our recommendations have been very consistent with travel.  You should have a pre-travel test.  You should quarantine for seven days.  You should have a post-travel test.  And then you should monitor for symptoms between 7 and 14 days.  We have been consistently discouraging travel, saying, “Please keep it limited to only essential travel.”

And what we’re seeing now is more travel than we saw — than we saw throughout the pandemic, including the Christmas and New Year’s holidays.  I think people have taken advantage of what they perceived as a relative paucity of cases, a relative lull in where we were, to take advantage of their time of spring break, of holiday travel.  And what I would just say is, you know, we’ve seen surges after every single holiday, and so — you know, July 4th, Labor Day, Christmas.  And we’re seeing the uptick of that right now.

So I would just sort of reiterate the recommendations from CDC, saying please limit travel to essential travel for the time being.

ACTING ADMINISTRATOR SLAVITT:  Your final question was about Johnson & Johnson doses.  And indeed, let me — to the premise of your question, Johnson & Johnson is due to deliver 11 million doses.  And as a single-dose regimen, that’s an enormous step forward for the country.

My message to the states, Tribes, and territories, and everyone else is: Get ready.  This is an enormous opportunity to vaccinate more people.  And tomorrow, we will be talking with the governors and others about how we’re going to split that up.


Next question.

MODERATOR:  Next, we’ll go to Kaitlan Collins with CNN.

Q    Thanks very much.  I have two questions.  One, if each of you could answer this: With the release of the World Health Organization report, can each of you say whether or not you trust the findings of this report?  Maybe “yes” or “no” or — to keep it short.

And then, secondly, to CDC Director Dr. Walensky, thank you for speaking so candidly about the data that you’re seeing, but of course that raises questions about restrictions that we are seeing be loosened in a lot of states.  And also, on the President’s call for 100 days of mask wearing, do you expect him to re-up that call or extend it past the 100 days given the numbers that you’re seeing?

ACTING ADMINISTRATOR SLAVITT:  Okay, Dr. Fauci, do you — would you like to go first on the WHO question?

DR. FAUCI:  Yeah, Kaitlan, I’d like to see that report first, and I also would like to inquire as to the extent in which the people who were on that group had access directly to the data that they would need to make a determination. 

Once I get that information, I’ll be able to more adequately answer whether I trust it or not.  But I want to read the report first, and then get a feel for what they — what they really had access to or did not have access to.

ACTING ADMINISTRATOR SLAVITT:  Dr. Walensky.

DR. WALENSKY:  Yeah, I don’t have much to add to what Dr. Fauci has said with regard to the report.  And simply to say as I, too, have not yet had an opportunity to see it.

With regard to the surging, we are working closely with the states.  I will be speaking with the governors tomorrow to try and reinforce the need for these — for current restrictions to not open up.  I think what we do with masking will really depend on where we are 40 days from now.

ACTING ADMINISTRATOR SLAVITT:  Yep.  And I would just add — it got to my inbox this morning, so I’m going to reserve judgment as well. 

Next question.

MODERATOR:  We have time for one more question.  We’ll go to Shannon Firth with MedPage Today.

Q    Hi, thank you for taking my question.  Dr. Walensky, I wondered if you could expand on what you said regarding substance use disorders and the concerns around exacerbating the risk of COVID-19 among those people.  Are there other groups that there’s increased risk of COVID outcomes, and are there any people that you’re taking off the list?  And how would that change any policies or recommendations going forward?

DR. WALENSKY:  Yeah, thank you for that.  I would invite you to, sort of, visit the list.  It’s sort of a more — a comprehensive review.  We do know that — we’ve seen data that folks who have substance use disorders have increased risk of severe disease.  There’s a medical review — a scientific review with that as well and an updated list of the scientific review of all the disorders that are — or the underlying conditions that may exacerbate COVID-19.

ACTING ADMINISTRATOR SLAVITT:  Thank you.  Thanks for those questions.  I invite everybody to tune into the President’s remarks later today.  And we will be doing this briefing again later in the week.  Thank you.

11:36 A.M. EDT

To view the COVID Press Briefing slides, visit https://www.whitehouse.gov/wp-content/uploads/2021/03/COVID-Press-Briefing_29March2021_For-Transcript.pdf

What should we think of vaccine pauses?

A gloved hand hitting the pause symbol

What to Make of Vaccine Pauses

A cautious, transparent response reveals a process committed to vaccine safety.

Q&A WITH DANIEL SALMON | APRIL 15, 2021

https://html5-player.libsyn.com/embed/episode/id/18394544/height/90/theme/custom/thumbnail/yes/direction/forward/render-playlist/no/custom-color/fb5600/


Public Health On Call

This conversation is an updated excerpt from the March 22 episode of Public Health On Call, in which Salmon spoke with Stephanie Desmon about the AstraZeneca situation in particular.Subscribe to Podcast

The U.S. on April 13 paused use of the Johnson & Johnson COVID-19 vaccine because, of the nearly 7 million people who received the vaccine, six women under 50 developed a rare form of blood clots called cerebral venous sinus thrombosis, or CVST.

This follows a similar move in Europe where several countries suspended use of the AstraZeneca COVID-19 vaccine because, of 17 million people in the EU and the UK who received the vaccine, 37 had CVST.

Daniel Salmon, PhD ’03, MPH, a professor in International Health and director of the Institute for Vaccine Safety, shares his take on what to make of such pauses.

How should we view these situations generally?

Bad things happen to people every day from a health perspective. People have heart attacks, people have strokes, people get infectious diseases, and chronic diseases, and cancer. People get hit by cars and shot by guns. And if you vaccinate people, these things will happen after people got the vaccine, by chance alone.

How frequently these things happen depends on the population. So, if we vaccinate a lot of people in a short amount of time, we have to anticipate that bad things will happen to them, hopefully at the same rate that would have happened anyway (except for the disease you’re vaccinating against, in this case COVID, which hopefully that happens less). The question is, is it because of the vaccine, and specifically [is it happening] more frequently after getting the vaccine? If, after you look at the data, you find that it still persists, usually you want to do a chart review and look for standardized case definitions and really do a more formal study.

The Johnson & Johnson and AstraZeneca vaccines were paused for the same reason. What are your thoughts on how these two situations have played out so far?

The situation with the J & J vaccine really requires more data. Ultimately, vaccine decisions are about weighing risks and benefits of the vaccine. Fortunately in the U.S. we have two other highly effective vaccines to use that have not raised similar safety concerns.

What do you make of the pauses in administering these vaccines?

Stopping the vaccine comes at a risk as well because those are people that aren’t getting vaccinated in the midst of a pandemic. But with that said, they want to be careful with safety and that’s a good thing. The availability of other vaccines makes this decision easier.

If this is in fact a pattern, you need to look at the risk of these blood clots among women in this age group and how much risk it is, and then compare it to the benefit of the vaccine. Because at the end of the day, it’s all about risk versus benefits. For example, flu vaccine causes Guillain-Barre syndrome in one to three per million people vaccinated. Guillain-Barre is a pretty serious neurological condition. However, it’s a one to three per million chance, and the benefits of the flu vaccine are far, far greater than that.

What does this say about the systems in place to find, report, and investigate any adverse events?

The systems are working because they identified something that looked unusual and they’re assessing it rapidly and making decisions from there. The decision to suspend it is a difficult judgment call. You don’t want to suspend something absent that reason, because it just confuses people, and potentially you’re not vaccinating people when you could.

Is this likely to hurt vaccine confidence and increase vaccine hesitancy?

You have to think about short term versus long term. In the short term this might cause some issues that may result in some people not getting vaccinated who would otherwise get vaccinated. But we’re not in it for the short term. We’re not going to eradicate COVID any time soon, if ever. We’re really fortunate to have multiple vaccines that look extremely good so quickly. It’s really a tremendous success.

This is about long-term trust and confidence in the system. And you can ask yourself, do you want a system that looks really hard for unusual, unexpected things; and, when it sees something weird, has really good science and scientists to investigate it to determine whether it just appears a little bit weird, or if it actually is weird; and if it is a problem, among whom and how frequently, so that when you and your doctor decide whether or not to get a vaccine, you have the best available information? Or would you rather they just not look and pretend it’s not there, and tell everybody it’s OK, and provide reassurance absent science, because if they did the science and told you about it, you might question it for a moment? I think the answer is clearly that people want the former.

Yes, there may be a short-term hit. And that has to be considered and words have to be chosen carefully. But we need a robust process. It needs to be objective, it needs to be driven by science, and it needs to be reasonably transparent. It doesn’t mean that every conversation should be put on the web, but the public needs to know that there are independent, credible, very competent people looking at issues carefully, and they’re taking a cautious approach. I know that’s what I want, and I think that’s what most people want.

RELATED CONTENT

Jon Kabat-Zinn “Full Catastrophe Living”: Thinking during meditation

“Thinking is not bad, nor is it even undesirable during meditation, What matters is whether you are aware of your thoughts and feelings during meditation and how you are in relationship to them. Trying to supress them will only result in greater tension and frustration and more problems, not in calmness, insight, clarity and peace. Meditation is not so concerned with how much thinking is going on as it is with how much room you are making it to take place within the field of your awareness from one moment to the next.”

Regional STEM Fairs Go Virtual with support of Youth Science Canada

The fair must go on…

Twenty-one regional STEM fairs go virtual, April 19 to 21,

with the support of Youth Science Canada

Students have one last chance to register their projects online; all others are invited to continue their STEM education through project-based learning at mystemspace.ca

OTTAWA, April 14, 2021 – Twenty-one regional science fairs will take place as one virtual fair, April 19 to 21, thanks to a partnership between Youth Science Canada and engineering.com, developers of the ProjectBoard Platform.

“The fairs must go on,” says Reni Barlow, executive director at Youth Science Canada. “This motto has been the driving force behind our efforts this year and I’m happy they’re paying off. By and large, our national STEM fair network has been successful in pivoting to help students continue to explore the world, tackle big problems and express their curiosity and ingenuity through project-based learning.”

Rather than creating a traditional poster or backboard, students post their projects on ProjectBoard, a fun and engaging platform developed by engineering.com in collaboration with Youth Science Canada. The platform allows students to share, discover, collaborate, document and receive feedback and recognition on their STEM projects, all online in a community-based and closely monitored setting.

Students are invited to provide information — why they chose to tackle the question or problem; how they went about answering the question or developing a solution; what they found out or developed; why the project matters or makes a difference; where they plan to take the project from here; plus references and a one-minute video.  Each student project is then reviewed by STEM professionals who also interview the students about their work. Top projects will be selected to participate in the virtual Canada-Wide Science Fair (CWSF) from May 19-21.

Students from the following 21 YSC-affiliated regions are eligible to register for the YSC Virtual Regional Science Fair:

·         Algoma Rotary, Ontario

·         Avon Maitland Huron Perth, Ontario

·         Canadian Rockies, Alberta

·         Cape Breton, Nova Scotia

·         Chignecto West, Nova Scotia

·         Conseil scolaire acadien provincial, Nova Scotia

·         Durham, Ontario

·         East Parry Sound, Ontario

·         Halifax, Nova Scotia

·         Island Lake, Manitoba

·         Kivalliq, Nunavut

·         North Bay, Ontario

·         Northern Saskatchewan

·         Northwest Saskatchewan

·         Omushkego, Ontario

·         Qikiqtaaluk, Nunavut

·         Sahtu, Northwest Territories

·         St. James Assiniboia, Manitoba

·         South East Saskatchewan

·         South Shore, Nova Scotia

·         Windsor, Ontario

Students can register their project at mystemspace.ca, under the “I have a project” link.

About Youth Science Canada

Youth Science Canada fuels the curiosity of Canadian youth through STEM projects. A registered charity incorporated in 1962, YSC delivers on its mission through national programs including mySTEMspace, the National STEM Fair Network, Canada-Wide Science Fair, STEM Expo, “Team Canada” representation at international fairs and Smarter Science professional development for teachers. Through these programs, YSC provides direct support to the more than 500,000 students who do STEM projects in any given year. For more information, visit youthscience.ca.

About engineering.com

Engineering.com is a global online publisher and discussion forum for problem solving, tech news, innovations and resources, with a simple mission to inspire engineering minds to be and do better. The company’s ProjectBoard platform, now powering Makeprojects.com, provides Makers and STEM communities a fun and engaging way to share ideas, develop projects and learn in groups online. For more information, please visit engineering.com.

How You Frame COVID Determines your Reaction to Public Health Initiatives: Can we say COVID ideology?

April 6, 2021

New Study Casts COVID-19 and Government Mandates in a New Light in Rural America

HOW PERSONAL VIEWS ON THE PANDEMIC AFFECT MASK WEARING AND OTHER PREVENTION BEHAVIORS

When Adam Koon, PhD, MPH, an assistant scientist at the Johns Hopkins Bloomberg School of Public Health, arrived in his wife’s hometown last summer to quarantine with their children, they were surprised to see so few people in masks. With his wife, Emily Mendenhall, PhD, MPH, a professor at Georgetown University, they set out to conduct a study in this small, rural Midwestern tourist town by interviewing local residents about COVID-19 and why so few took COVID-19 precautions seriously. The study was published in Social Science & Medicine in March 2021. According to Koon, “As a research team, we were motivated by an equal mix of concern and curiosity about a community we love dearly. Most of the team grew up in the area and the rest either live there or spend a considerable amount of time there. On a tacit level, we understood some of what was going on, but I think we learned several new things along the way.”  Midwestern Tourist Town
Photo credit: David Thoreson

At the beginning of the pandemic, the town shut down for approximately one month, and then reopened without any public health mandates in place for social distancing, masking and closures on May 1, 2020, at the outset of the popular tourist season. Although the community was mostly white, conservative, and Christian, people held widely different views that cut across political, religious, and class affiliations. “We found that when the tourist season came, people shifted their collective priorities away from the novel coronavirus to focus on saving the economy because the 100 days of summer are the only months when many locals earn income,” Mendenhall said. Yet, the researchers wanted to go further by understanding how a variety beliefs and values were tied to actions. 

Framing is a fundamental concept in the social sciences that explains how moral worldviews are constructed. Differences in framing contested issues, such as gun control and abortion, lie at the heart of policy controversy. This helps us understand, in part, how people make sense of the world around them and their relationships in which health becomes embedded. According to Koon, “I often use a particular form of framing analysis that looks more at the policymaking process, but in this instance it made sense to focus on the frames themselves. In some ways, this is kind of a classic sociological approach to frame analysis, but we also drew a little bit on some newer theories of framing from critical policy studies.” Koon’s expertise on framing and Mendenhall’s skill as an ethnographer allowed them to rapidly explore these complicated processes.

The researchers collected data through semi-structured interviews with local community members from June to August 2020. They also observed community meetings, events, and daily life. The researchers found four main frames that enabled individuals to make sense of the coronavirus: concern, crisis, constraint, and conspiracy:

  • Concern frames focused on how some people are uniquely affected by COVID-19 (e.g. the elderly, people with co-morbidities, or front-line workers) and as a result, these individuals were likely to take preventive actions, especially to protect themselves and loved ones. 
  • Crisis frames recognized coronavirus as a pervasive and profound threat requiring unprecedented action. Individuals with this frame were likely to follow science and public health recommendations closely. 
  • Constraint frames emphasized the coronavirus response as a threat to financial stability and personal growth that should be resisted. Individuals with this frame were likely to be business owners and employees more concerned about economic implications than the biological threat, or younger people who perceived the threat of COVID-19 to be minimal to themselves but with a big impact on their social lives.
  • Conspiracy frames denied its biological basis and did not compel action. Individuals with this frame were likely to have a strong anti-government sentiment and unwillingness to follow public health recommendations. 

The frames constructed around COVID-19 in this small Midwestern tourist town matter. For example, residents who subscribed to a concern frame often felt socially obligated to comply with COVID-19 safety guidance in the absence of government mandates if it only directly affected themselves or their families and not the broader community, whereas constraint and conspiracy frame adherents were much more resistant. This allowed COVID-19 to thrive and spread rapidly, as there was neither a coherent appreciation of the biological risk nor widespread adoption of control measures used in this community. These frames help to explain the controversy surrounding COVID-19, even in settings with fewer obvious political, ethnic, and class distinctions. “This is not a blue state–red state thing. We’re not talking party politics,” said Koon. “The study helps us understand why COVID-19 guidelines have been so inconsistent and divisive even in less diverse settings. These findings provide a social rationale for public health mandates—such as masking, school and business closures, and social distancing—when contested beliefs impede collective action,” he added.  

The research team is currently using this evidence to advise targeted communication and outreach efforts that seek to reframe the pandemic response in ways that resonate with greater segments of the population. In this way, they hope policymakers will be better positioned to strengthen guidance on measures to prevent viral transmission. According to Koon, “We still have more work to do, and Emily’s writing a wonderful book on the subject, but we’re pleased that we’re able to contribute in this small way.”

The study was published in Social Science & Medicine in March 2021 and written by Adam D. Koon, Emily Mendenhall, Lori Eich, Abby Adams, and Zach A. Borus. Koon and Mendenhall also wrote a companion piece with Nora Kenworthy drawing on the same data to look at the cultural politics of the American COVID-19 response. It was recently published in Global Public Health. The research for both papers was not funded by any organization and done entirely for free. 

Johns Hopkins Bloomberg School of Public Health

United States Puts Hold of J&J Vaccine

Joint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine

The following statement is attributed to Dr. Anne Schuchat, Principal Deputy Director of the CDC and Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and ResearchEspañol (Spanish)Media Statement

For Immediate Release: Tuesday, April 13, 2021
Contact: Media Relations
(404) 639-3286

As of April 12, more than 6.8 million doses of the Johnson & Johnson (Janssen ) vaccine have been administered in the U.S. CDC and FDA are reviewing data involving six reported U.S. cases of a rare and severe type of blood clot in individuals after receiving the J&J vaccine. In these cases, a type of blood clot called cerebral venous sinus thrombosis (CVST) was seen in combination with low levels of blood platelets (thrombocytopenia). All six cases occurred among women between the ages of 18 and 48, and symptoms occurred 6 to 13 days after vaccination. Treatment of this specific type of blood clot is different from the treatment that might typically be administered. Usually, an anticoagulant drug called heparin is used to treat blood clots. In this setting, administration of heparin may be dangerous, and alternative treatments need to be given.

CDC will convene a meeting of the Advisory Committee on Immunization Practices (ACIP) on Wednesday to further review these cases and assess their potential significance. FDA will review that analysis as it also investigates these cases. Until that process is complete, we are recommending a pause in the use of this vaccine out of an abundance of caution. This is important, in part, to ensure that the health care provider community is aware of the potential for these adverse events and can plan for proper recognition and management due to the unique treatment required with this type of blood clot.

Right now, these adverse events appear to be extremely rare. COVID-19 vaccine safety is a top priority for the federal government, and we take all reports of health problems following COVID-19 vaccination very seriously. People who have received the J&J vaccine who develop severe headache, abdominal pain, leg pain, or shortness of breath within three weeks after vaccination should contact their health care provider. Health care providers are asked to report adverse events to the Vaccine Adverse Event Reporting System at https://vaers.hhs.gov/reportevent.htmlexternal icon.

CDC and FDA will provide additional information and answer questions later today at a media briefing. A recording of that media call will be available on the FDA’s YouTube channel.

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CDC works 24/7 protecting America’s health, safety and security. Whether disease start at home or abroad, are curable or preventable, chronic or acute, or from human activity or deliberate attack, CDC responds to America’s most pressing health threats. CDC is headquartered in Atlanta and has experts located throughout the United States and the world.